Molecular Pharmacology: From DNA to Drug Discovery

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Author: John Dickenson

Pages: 424

Size: 3.295,02 Kb

Publication Date: January 22,2013

Category: Molecular



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This textbook offers a fresh, extensive and accessible launch to the rapidly growing field of molecular pharmacology. Adopting a medication target-based, as opposed to the traditional organ/program based, strategy this innovative guidebook reflects the existing advances and research craze towards molecular based medication design, produced from a detailed knowledge of chemical responses in your body. Drugs are after that tailored to match a treatment profile, as opposed to the traditional approach to ‘trial and error’ medication discovery which targets testing chemicals on pets or cellular cultures and complementing their effects to remedies.

  • Applied - includes many, real-world examples and an in depth case-research based chapter which talks about current and possible long term treatment approaches for cystic fibrosis. latest advances and advancements in the four main human drug target family members (G-proteins coupled receptors, ion stations, nuclear receptors and transporters), cloning of medication targets, transgenic pet technology, gene therapy, pharmacogenomics and talks about the function of calcium in the cellular. This research study considers the relative merits of both medication therapy for particular classes of mutation and gene therapy to improve the underlying defect.
  • LEADING EDGE - highlights advancements in pharmacogenomics and explores how an specific’s genetic make-up influences their response to therapeutic medications and the prospect of harmful unwanted effects.

    Providing a great source for advanced under-graduate and MSc/PhD students, brand-new experts to the field and practitioners for continuing professional advancement, Molecular Pharmacology explores;

    • Current - targets leading edge techniques and techniques, including new solutions to quantify biological actions in various systems and methods to interpret and understand pharmacological data.
  • Available - includes a comprehensive glossary, ideas for further reading by the end of every chapter and an connected website that delivers a complete group of statistics from within the publication.


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