Pharmaceutical Process Chemistry for Synthesis: Rethinking the Routes to Scale-Up

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Pages: 376

Size: 2.346,92 Kb

Publication Date: February 15,2011

Category: Physical & Theoretical



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There is a have to explain that generic versions of a drug might not be manufactured by the same process simply because brand-name drugs and that the various processes may have significantly different environmental impacts.

Providing insights about process path selection, selection of reagents, and response conditions, Pharmaceutical Procedure Chemistry for Synthesis guides procedure chemists in identifying greatest processes for developing these blockbuster drugs because they lose patent safety. Further, it highlights the strategies and methodology that could be useful for expediting the procedure research and advancement of the blockbusters into the future. Two global forces are in odds today—the drive for “greener” procedures and the drive for lower medication prices. This book provides this conflict into razor-sharp focus by discussing at length the published procedure chemistry for top-selling little molecule medicines.

Created from a refreshingly objective perspective, this publication is essential for procedure chemists who have to devise useful syntheses for increasingly complicated drugs in a continuously decreasing timeframe.



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